How Long Do You Stay on
Semaglutide for Weight Loss?
Losing weight is not easy for everyone. In fact, millions of people around the globe struggle to shed weight by eating and exercising alone. This is why exploring alternative treatment options could make all the difference if you’ve struggled to shed extra pounds despite your best efforts.
One effective option to consider is Semaglutide, a medication known for suppressing appetite and supporting significant weight loss. Many people begin seeing results in as little as four weeks, but you may wonder, How long do you stay on Semaglutide for weight loss? This varies by individual, as your healthcare provider will tailor the treatment duration to help you achieve and maintain your goals.
Here’s a closer look at Semaglutide, what it is, how it works, the clinical trials, and what you can expect during your GLP-1 journey in terms of weight loss:
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First, What is Semaglutide?
Developed initially to manage Type 2 diabetes, Semaglutide has recently gained popularity as an aid for weight loss. This medication works by suppressing appetite and improving glucose control, which can support weight loss efforts where diet and exercise fail. Semaglutide mimics the GLP-1 hormone, a natural substance that helps regulate insulin, hunger, and metabolism.
What Is Semaglutide Used For?
Semaglutide is primarily used to help individuals with Type 2 diabetes manage their blood glucose levels. Because stable glucose levels can contribute to weight loss, the medication has also been recognized for its potential as a weight management tool. Its additional benefits, such as appetite suppression and reduced food cravings, can further support weight loss goals. Whether taken for diabetes or as part of a weight loss plan, Semaglutide can offer both a physical and mental boost as individuals start seeing positive changes in their body, mind, and life.
Related Reading: Semaglutide vs Tirzepatide. Learn the Differences Between Medications>>
How Does Semaglutide Work?
The action of Semaglutide is relatively straightforward. When introduced to the body, Semaglutide mimics the GLP-1 hormone, leading to hormonal changes that impact appetite, cravings, and digestion. These gradual changes help reduce food intake, making eating smaller portions easier and avoiding frequent snacking. This is why Semaglutide has become a popular option for obesity treatment, as it promotes a steady, sustainable approach to weight loss.
Related Reading: Read All about the Semaglutide Pros and Cons Here>>
Semaglutide and Weight Loss in Clinical Trials
Semaglutide has shown incredible results in clinical trials, with most participants staying on the medication for at least 68 weeks. During this time, people saw substantial weight loss—often over 10-15% of their starting weight. Not only did Semaglutide help with weight reduction, but it also had positive effects on blood sugar, blood pressure, and other health markers, making it ideal for people with type 2 diabetes or weight-related health concerns.
One of the most notable studies, a clinical trial published in The New England Journal of Medicine in 2021, known as the STEP 1 trial, examined the effectiveness of Semaglutide 2.4 mg for weight management in nearly 2,000 adults with excess weight or obesity. Some of these participants had even undergone bariatric surgery before trying Semaglutide.
Here’s what researchers found during the 68-week trial:
- Significant Weight Loss: These participants taking Semaglutide lost an average of 14.9% of their starting weight, compared to just 2.4% for those on a placebo.
- High Success Rate: In the Semaglutide group, 86% lost at least 5% of their weight, and 75% lost at least 10%.
- Improved Health Markers: The treatment also reduced waist circumference, blood pressure, and triglycerides, along with better blood sugar control and quality of life.
- Generally Well-Tolerated: The most common side effects were mild to moderate gastrointestinal symptoms like nausea and diarrhea, which typically eased over time.
The results from this study were groundbreaking, making Semaglutide, the active ingredient in compounded Semaglutide, Wegovy, and Ozempic, a go-to choice for weight management. The FDA has since approved it for chronic weight management in adults with excess weight or obesity, giving hope to those looking for a medical boost in their weight loss journey.
Your Weight Loss Timeline withSemaglutide Based on Clinical Trials*
After 4 Weeks
Most people notice some weight loss within the first month of starting Semaglutide. Although results vary by individual, the STEP 1 trial found that participants lost an average of 3.8% of their starting weight after four weeks on the 2.4 mg dose.
After 12 Weeks
Weight loss typically becomes more noticeable by the three-month mark. In the STEP 1 trial, participants on the 2.4 mg dose lost an average of 9.6% of their initial weight, compared to only 2.8% in the placebo group.
After 6 Months
At six months, the progress continues with impressive results. Those in the trial who took Semaglutide 2.4 mg had lost an average of 13.8% of their initial weight, while the placebo group lost just 3.7%.
After 12 Months
After a full year on Semaglutide and lifestyle changes, participants generally lost 15-17% of their starting weight. Some achieved even higher results—losing over 20%—while others saw a more moderate reduction of 5-10%.
When Weight Loss May Plateau
For many, weight loss with Semaglutide may begin to stabilize around 9 to 12 months. Those who stick with both the medication and lifestyle recommendations tend to sustain a loss of around 10-15% over 1 to 2 years.
However, individual results will vary, with some experiencing more gradual or extensive changes over time.*
Related Reading: Switching from Semaglutide to Tirzepatide? Here’s what to expect>>
How to Support Optimal Weight Loss While Taking Semaglutide
Combining the medication with healthy habits ensures you get the most out of Semaglutide for weight loss. In fact, healthy changes can help you see even better results and maintain them longer-term.
Here are some tips to help you maximize weight loss while taking Semaglutide:
1. Follow a Balanced, Protein-Rich Diet
- Focus on Protein: Aim for lean protein sources like chicken, turkey, fish, eggs, and plant-based options like beans and lentils. Protein can help keep you fuller for longer, making it easier to manage your appetite.
- Incorporate Healthy Fats: Include healthy fats, such as avocados, nuts, seeds, and olive oil, which can promote satiety and support metabolism.
- Prioritize Fiber-Rich Foods: Add plenty of fiber to your meals with whole grains, fruits, and vegetables. Fiber aids digestion and helps you feel full longer.
- Limit Processed Foods and Sugars: Minimize foods high in added sugars and refined carbohydrates, which can lead to blood sugar spikes and increased cravings.
2. Create a Realistic Exercise Routine
- Incorporate Both Cardio and Strength Training: Cardiovascular exercises like walking, jogging, cycling, or swimming can help burn calories, while strength training builds muscle and supports metabolism. Aim for a balance of both types each week.
- Set Small, Achievable Goals: Start with a goal you can realistically stick to, such as 30 minutes of exercise a few days a week, and gradually increase as your fitness level improves.
- Stay Consistent: Consistency, whether a daily walk or a quick home workout, is key. Regular movement supports weight loss and improves mood and energy levels.
3. Focus on Mindful Eating
- Practice Portion Control: Pay attention to portion sizes, especially when eating calorie-dense foods. Using smaller plates or bowls can help with managing portions without feeling deprived.
- Eat Slowly and Savor Each Bite: Eating slowly allows you to enjoy your food and gives your body time to signal fullness, reducing the likelihood of overeating.
Combining Semaglutide with healthier lifestyle habits can help you achieve steady, sustainable weight loss and maintain the results for the long term. Remember, consistency is key, and small, healthy changes over time can lead to lasting success.
Try Semaglutide for Weight Loss Near Me
If you live in or around Fall River, Greater Providence, Newport County, and the south coast of MA and want to learn exactly how long you should take Semaglutide for weight loss, contact Slim by TRYM. We are proud to be the leading provider of GLP-1 medications in Fall River, including Semaglutide and Tirzepatide. Call us at (774) 252-8239 or fill out the form below to schedule your weight loss consultation and discover which once-weekly injection is the best for your body, health, and weight loss goals.
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Hannah M.
Dr. Lowney and his team are amazing, super attentive. A great space where I was very well attended, I recommend it.
Hannah M.
Dr. Lowney & his entire staff truly make you feel like family!!! So warm and loving. The results are truly life-changing, and there is nothing better than loving the way you look!!! He lives up to his name, he honestly is & forever will be Dr. “Feel Good” ❤️ his work speaks for itself. All around amazing
Hannah M.
Love Dr. Lowney and his wonderful staff! Had the best experience, and I will definitely be a lifelong client. After spending many years in the gym, Dr. Lowney gave me the results that I was working so hard for.
Hannah M.
Dr. Lowney is the best. The staff is also very nice and helpful. I am very happy with my results, and I highly recommend them!!
Hannah M.
Dr. Lowney and his team are amazing, super attentive. A great space where I was very well attended, I recommend it.
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